| Date | Player | Hits | |
| 05/23/1886 | Joe Watlington | 6 Hits in 6 AB, 1 RBI versus Birmingham while playing for New Orleans | |
| 09/27/1887 | Ed Treadwell | 6 Hits in 6 AB, 1 HR and 4 RBI versus Richmond while playing for Knoxville | |
| 06/13/1890 | Oscar Kirby | 6 Hits in 6 AB, 2 HR and 5 RBI versus Knoxville while playing for Richmond | |
| 05/04/1896 | Denny McClister | 6 Hits in 7 AB, 0 RBI versus Richmond while playing for New Orleans | |
| 05/20/1900 | Walt McGee | 6 Hits in 9 AB, 1 RBI versus Louisville while playing for Knoxville | |
| 06/14/1900 | Jack Corbett | 6 Hits in 6 AB, 7 RBI versus New Orleans while playing for Nashville | |
| 06/22/1900 | Jack McSorley | 6 Hits in 7 AB, 2 RBI versus Knoxville while playing for Nashville | |
| 07/14/1900 | Tom Moran | 6 Hits in 6 AB, 2 RBI versus New Orleans while playing for Memphis | |
| 06/23/1901 | Rufus Thomas | 6 Hits in 8 AB, 3 RBI versus Knoxville while playing for Richmond | |
| 05/26/1903 | Rudy Crawford | 6 Hits in 7 AB, 1 RBI versus Birmingham while playing for Nashville | |
